USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9Y4L1 USC-OGP 2-DE database:  Q9Y4L1 Q9Y4L1 General information about the entry View entry in simple text format Entry name HYOU1_HUMAN Primary accession number Q9Y4L1 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Hypoxia up-regulated protein 1; AltName: Full=150 kDa oxygen-regulated protein; Short=ORP-150; AltName: Full=170 kDa glucose-regulated protein; Short=GRP-170; Flags: Precursor;. Gene name Name=HYOU1 Synonyms=GRP170, ORP150 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1096: pI=5.26; Mw=148284 Cross-references UniProtKB/Swiss-Prot Q9Y4L1; HYOU1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name HYOU1_HUMAN Primary accession number Q9Y4L1 Secondary accession number(s) A8C1Z0 B7Z909 Q2I204 Q53H25 Sequence was last modified on  November 1, 1999 (version 1) Annotations were last modified on  March 15, 2017 (version 164) Name and origin of the protein Description RecName: Full=Hypoxia up-regulated protein 1; AltName: Full=150 kDa oxygen-regulated protein; Short=ORP-150; AltName: Full=170 kDa glucose-regulated protein; Short=GRP-170; Flags: Precursor; Gene name Name=HYOU1 Synonyms=GRP170, ORP150 Encoded on Name=HYOU1; Synonyms=GRP170, ORP150 Keywords Acetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Nucleotide-binding; Phosphoprotein; Reference proteome; Signal; Stress response. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U65785; AAC50947.1; -; mRNA EMBL AB009979; BAF80348.1; -; Genomic_DNA EMBL DQ350134; ABC75106.1; -; mRNA EMBL DQ372932; ABD14370.1; -; mRNA EMBL AK304264; BAH14145.1; -; mRNA EMBL AK314178; BAG36860.1; -; mRNA EMBL AK222756; BAD96476.1; -; mRNA EMBL EF444986; ACA06002.1; -; Genomic_DNA EMBL AP003392; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS CCDS8408.1; -. [Q9Y4L1-1]; . PIR JC5278; JC5278; . RefSeq NP_001124463.1; NM_001130991.2. [Q9Y4L1-1]; . RefSeq NP_006380.1; NM_006389.4. [Q9Y4L1-1]; . RefSeq XP_016872585.1; XM_017017096.1. [Q9Y4L1-1]; . RefSeq XP_016872586.1; XM_017017097.1. [Q9Y4L1-1]; . UniGene Hs.277704; -; . ProteinModelPortal Q9Y4L1; -; . SMR Q9Y4L1; -; . BioGrid 115780; 70; . IntAct Q9Y4L1; 28; . MINT MINT-4105974; -; . STRING 9606.ENSP00000384144; -; . ChEMBL CHEMBL2216741; -; . iPTMnet Q9Y4L1; -; . PhosphoSitePlus Q9Y4L1; -; . SwissPalm Q9Y4L1; -; . BioMuta HYOU1; -; . DMDM 10720185; -; . REPRODUCTION-2DPAGE IPI00000877; -; . EPD Q9Y4L1; -; . PaxDb Q9Y4L1; -; . PeptideAtlas Q9Y4L1; -; . PRIDE Q9Y4L1; -; . Ensembl ENST00000617285; ENSP00000480150; ENSG00000149428. [Q9Y4L1-1]; . Ensembl ENST00000630669; ENSP00000486825; ENSG00000280682. [Q9Y4L1-1]; . GeneID 10525; -; . KEGG hsa:10525; -; . UCSC uc031yhc.2; human. [Q9Y4L1-1]; . CTD 10525; -; . DisGeNET 10525; -; . GeneCards HYOU1; -; . HGNC HGNC:16931; HYOU1; . HPA HPA049296; -; . MIM 601746; gene; . neXtProt NX_Q9Y4L1; -; . OpenTargets ENSG00000149428; -; . PharmGKB PA38427; -; . eggNOG KOG0104; Eukaryota; . eggNOG COG0443; LUCA; . GeneTree ENSGT00840000129925; -; . HOGENOM HOG000007865; -; . HOVERGEN HBG106402; -; . InParanoid Q9Y4L1; -; . KO K09486; -; . OMA RKQRMVE; -; . OrthoDB EOG091G025X; -; . PhylomeDB Q9Y4L1; -; . TreeFam TF105048; -; . Reactome R-HSA-3000484; Scavenging by Class F Receptors; . Reactome R-HSA-381038; XBP1(S) activates chaperone genes; . ChiTaRS HYOU1; human; . GeneWiki HYOU1; -; . GenomeRNAi 10525; -; . PMAP-CutDB Q9Y4L1; -; . PRO PR:Q9Y4L1; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000149428; -; . CleanEx HS_HYOU1; -; . ExpressionAtlas Q9Y4L1; baseline and differential; . Genevisible Q9Y4L1; HS; . GO GO:0071682; C:endocytic vesicle lumen; TAS:Reactome; . GO GO:0005783; C:endoplasmic reticulum; NAS:ParkinsonsUK-UCL; . GO GO:0034663; C:endoplasmic reticulum chaperone complex; IEA:Ensembl; . GO GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005790; C:smooth endoplasmic reticulum; ISS:ParkinsonsUK-UCL; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0051087; F:chaperone binding; ISS:ParkinsonsUK-UCL; . GO GO:0071456; P:cellular response to hypoxia; IDA:ParkinsonsUK-UCL; . GO GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:ParkinsonsUK-UCL; . GO GO:0036498; P:IRE1-mediated unfolded protein response; TAS:Reactome; . GO GO:1903382; P:negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway; IEA:Ensembl; . GO GO:1903298; P:negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway; IDA:ParkinsonsUK-UCL; . GO GO:0006898; P:receptor-mediated endocytosis; TAS:Reactome; . GO GO:0034976; P:response to endoplasmic reticulum stress; IEP:ParkinsonsUK-UCL; . GO GO:0002931; P:response to ischemia; ISS:ParkinsonsUK-UCL; . Gene3D 1.20.1270.10; -; 1; . Gene3D 2.60.34.10; -; 1; . InterPro IPR018181; Heat_shock_70_CS; . InterPro IPR029048; HSP70_C; . InterPro IPR029047; HSP70_peptide-bd; . InterPro IPR013126; Hsp_70_fam; . Pfam PF00012; HSP70; 1; . PRINTS PR00301; HEATSHOCK70; . SUPFAM SSF100934; SSF100934; 1; . PROSITE PS00329; HSP70_2; 1; . PROSITE PS01036; HSP70_3; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]